Genomics of Foodborne Bacterial Pathogens

1.4 Impacts of Comparative and Functional Genome Analyses on Food Safety The use of genome sequence data has clearly impacted food safety, including the development of new technologies and assays that are routinely used to detect and ...

Author: Martin Wiedmann

Publisher: Springer Science & Business Media

ISBN: 9781441976864

Category: Science

Page: 524

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Foodborne illnesses caused by various bacterial, viral, and fungal pathogens lead to a high number of morbidity and mortality in the U.S. and throughout the world. Recent advances in microbial genomics have significantly improved our understanding of the physiology, evolution, ecology, epidemiology, and pathogenesis of different foodborne pathogens. This book focuses on the genomics of foodborne bacterial pathogens. It begins with a brief overview of the recent advances in microbial genomics and the impact of genomics on food safety research. Then, eight chapters follow that elaborate some in-depth reviews on the genomics of several common foodborne bacterial pathogens including Bacillus, Campylobacter, Clostridium, Escherichia coli, Listeria, Salmonella, Staphylococcus, and Vibrio. Finally, the last four chapters focus on some current genomic, transcriptomic, and proteomic technologies and their applications in studying the epidemiology, evolution, and pathogenesis of foodborne bacterial pathogens. Genomics of Foodborne Bacterial Pathogens can be used as a reference by scientists and professionals in academia, government, and industry who are interested in understanding microbial genomics and using genomics tools to study foodborne bacterial pathogens. This book can also be used as a textbook for instructors and professors who teach food microbiology or microbial genomics-related courses at the post-graduate level.
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Applications of Whole Genome Sequencing in food safety management

TECHNICAL BACKGROUND PAPER Food and Agriculture Organization of the United Nations, World Health Organization. identification of Escherichia coli O157:H7 by coupling genomic data with in vitro adherence to human epithelial cells.

Author: Food and Agriculture Organization of the United Nations

Publisher: Food & Agriculture Org.

ISBN:

Category: Health & Fitness

Page: 29

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Food safety is a global concern, and consumers have the right to safe and nutritious food (FAO, 1996). Considerable efforts to strengthen food control systems have been made in many countries. However, while progress has been made, the estimated global burden of foodborne diseases: 600 million foodborne illnesses and 420 000 deaths from 31 major food safety hazards in 2010 (WHO, 2015)1 and the related social and economic costs (loss of income, employment and market access) remain unacceptably high. In addition, food safety is an important element in achieving food security, which is negatively impacted by both the health and economic aspects of unsafe food. Within this context, there are ongoing efforts in the way in which the building blocks of food control systems are developed and implemented, from legislative aspects to surveillance and monitoring programmes, and the tools used by laboratories. Whole Genome Sequencing (WGS) has recently emerged as a new tool, and offers great potential in the way we investigate, assess and manage microbiological food safety issues and illnesses. It allows the identification and characterization of micro-organisms with a level of precision not previously possible, therefore potentially minimizing much of the uncertainty which impacts our ability to respond and manage microbiological food safety issues effectively and efficiently. This, in addition to its rapidly declining costs, increases the attractiveness of incorporating such a tool in food safety management. While several industrialized countries have been moving forward with the technology, its application is limited, particularly in developing and transitional countries. Information describing the potential benefits, possible drawbacks, infrastructure requirements and technical challenges is urgently needed if countries are to make appropriate decisions about when and where to use this technology to strengthen national food control systems.
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Advances in Microbial Food Safety

Bioinformatics is the use of statistical and computational approaches to analyze, manage and store genomic, proteomic and other omic ... including whole genome sequencing, are having a great impact on food microbiology and food safety.

Author: J Sofos

Publisher: Elsevier

ISBN: 9780857098740

Category: Technology & Engineering

Page: 560

View: 758

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New research, outbreaks of foodborne disease and changes to legislation mean that food microbiology research is constantly evolving. Advances in microbial food safety: Volume 1 summarises the key trends in this area for the food industry. The book begins with an introductory chapter discussing food safety management systems from the past to the present day and looking to future directions. The book moves on to provide updates on specific pathogens including Salmonella, Listeria monocytogenes and Bacillus species. New developments in the area are explored with chapters on emerging parasites in food, advances in separation and concentration of microorganisms from food samples, new approaches in microbial pathogen detection, and an update on novel methods for pathogen control in livestock preharvest. With its distinguished editor and international team of expert contributors, Advances in microbial food safety: Volume 1 is a standard reference for researchers, consultants and managers in the food industry responsible for food safety, analytical laboratories testing the safety of the food we eat, and researchers in academia working on food microbial safety. Summarises new research, outbreaks of foodborne disease and changes to legislation in food microbiology research Examines past, present and future food safety management systems Provides updates on specific pathogens including Salmonella, Listeria monocytogenes and Bacillus species
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Food Safety and Public Health

MJ, CY, PK, LZ, HF, YJ, LS, HC, BL, QC, YW, YG, YS, REFERENCES Allard, M. W., Bell, R., Ferreira, C. M., Gonzalez-Escalona, N., Hoffmann, M., Muruvanda, T., et al. (2018). Genomics of foodborne pathogens for microbial food safety. Curr.

Author: Yosra A. Helmy

Publisher: Frontiers Media SA

ISBN: 9782832504673

Category: Science

Page: 351

View: 144

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Applied Genomics of Foodborne Pathogens

Response System (EWRS) [123] and Rapid Alert System for Food and Feeds (RASFF; http://ec.europa.eu/food/safety/rasff/index_en.htm), NoroNet, and WHO networks among others. In addition to these existing systems, there is a multitude of ...

Author: Xiangyu Deng

Publisher: Springer

ISBN: 9783319437514

Category: Technology & Engineering

Page: 205

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This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential in studying, surveying and controlling foodborne microbial pathogens. The vast opportunities brought by this trend are often at odds with the lack of bioinformatics know-how among food safety and public health professionals, since such expertise is not part of a typical food microbiology curriculum and skill set. Further complicating the challenge is the large and ever evolving body of bioinformatics tools that can obfuscate newcomers to this area. Although reviews, tutorials and books are not in short supply in the fields of bioinformatics and genomics, until now there has not been a comprehensive and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts at the forefront of foodborne pathogen genomics research.
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Advances in microbial food safety

Advances in genomics and proteomics-based methods for the study of foodborne bacterial pathogens P. Fratamico, N.W. Gunther. including diarrheagenic Escherichia coli, Salmonella enterica ssp. enterica serotypes, Listeria monocytogenes, ...

Author: P. Fratamico

Publisher: Elsevier Inc. Chapters

ISBN: 9780128089828

Category: Technology & Engineering

Page: 560

View: 797

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Omic technologies, including genomics, proteomics and metabolomics, are used to study pathogen behavior at the molecular level and develop improved pathogen detection and typing systems. Omic technologies analyze complete or nearly complete expressions of cell functions. DNA sequencing has resulted in complete genomes of foodborne pathogens. Omic-based technologies explore biological processes in a quantitative and integrative manner. They facilitate identification of genes and proteins that contribute to survival and persistence in food and other environments, that play a role in pathogenesis and that are targets for detection methods and control strategies. Challenges that remain are performing genomic and proteomic studies in food and other complex matrices and interpreting and analyzing the data produced from these investigations to enhance food safety.
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Applied Genomics of Foodborne Pathogens

This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens.

Author: Xiangyu Deng

Publisher: Springer

ISBN: 3319437496

Category: Science

Page: 254

View: 659

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This book provides a timely and thorough snapshot into the emerging and fast evolving area of applied genomics of foodborne pathogens. Driven by the drastic advance of whole genome shot gun sequencing (WGS) technologies, genomics applications are becoming increasingly valuable and even essential in studying, surveying and controlling foodborne microbial pathogens. The vast opportunities brought by this trend are often at odds with the lack of bioinformatics know-how among food safety and public health professionals, since such expertise is not part of a typical food microbiology curriculum and skill set. Further complicating the challenge is the large and ever evolving body of bioinformatics tools that can obfuscate newcomers to this area. Although reviews, tutorials and books are not in short supply in the fields of bioinformatics and genomics, until now there has not been a comprehensive and customized source of information designed for and accessible to microbiologists interested in applying cutting-edge genomics in food safety and public health research. This book fills this void with a well-selected collection of topics, case studies, and bioinformatics tools contributed by experts at the forefront of foodborne pathogen genomics research.
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Preharvest Food Safety

Recent European Food Safety Authority scientific opinions on Salmonella contamina- tion of melons and tomatoes also offer ... for genomic sequencing in food safety research (http://www.fda.gov/ Food/FoodScienceResearch/WholeGenome ...

Author: Siddhartha Thakur

Publisher: John Wiley & Sons

ISBN: 9781555819644

Category: Technology & Engineering

Page: 426

View: 448

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An overview of farm-to-fork safety in the preharvest realm Foodborne outbreaks continue to take lives and harm economies, making controlling the entry of pathogens into the food supply a priority. Preharvest factors have been the cause of numerous outbreaks, including Listeria in melons, Salmonella associated with tomatoes, and Shiga toxin-producing E.coli in beef products, yet most traditional control measures and regulations occur at the postharvest stage. Preharvest Food Safety covers a broad swath of knowledge surrounding topics of safety at the preharvest and harvest stages, focusing on problems for specific food sources and food pathogens, as well as new tools and potential solutions. Led by editors Siddhartha Thakur and Kalmia Kniel, a team of expert authors provides insights into critical themes surrounding preharvest food safety, including Challenges specific to meat, seafood, dairy, egg, produce, grain, and nut production Established and emerging foodborne and agriculture-related pathogens Influences of external factors such as climate change and the growing local-foods trend Regulatory issues from both US and EU perspectives Use of pre- and probiotics, molecular tools, mathematical modeling, and one health approaches Intended to encourage the scientific community and food industry stakeholders to advance their knowledge of the developments and challenges associated with preharvest food safety, this book addresses the current state of the field and provides a diverse array of chapters focused on a variety of food commodities and microbiological hazards.
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Microbial Biotechnology in Food and Health

Applying microbial genomic research, a food sample can easily be tested for the presence of those genes, ... genomics. tool. to. increase. food. safety. Since foodborne pathogens represent a serious threat to food safety and public ...

Author: Ramesh C. Ray

Publisher: Academic Press

ISBN: 9780128227619

Category: Technology & Engineering

Page: 308

View: 832

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Microbial Biotechnology in Food and Health Science, volume one in the Applied Biotechnology Reviews series, offers two unique sections within the theme of genomics and bioprocessing and the bioengineering of microorganisms in the role of food science and human health. This volume provides review articles as the basis supporting biotechnological research useful to a wide scope of research initiatives. Important relevant information on genomics, proteomics and metabolomics are included as well as the emerging interdisciplinary area of synthetic biology which enables the metabolic engineering of microorganisms to produce pharmaceuticals. Applied Biotechnology Reviews is a series aimed at bringing all aspects of biotechnology as it is applied to food science – from agriculture through product processing into focus through topical volumes. Each volume will cover a relevant application approach in industrial biotechnology. Covers the latest biotechnological research articles on applications of microbes for food and health science Presents research articles to emphasize research methods and techniques useful for research outcomes Analysis detoxification properties of microorganisms in foods Includes methods of bioengineering of microbes to improve human insulin synthesis/recombinant protein
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